CND10

1. Product Catalog Code: CND10
2. Chemical Name:CND10
3. Specification: 10mg per vial
4. Appearance: White sterile lyophilized polypeptide powder
5. Purity: Research grade ≥99% (HPLC verification)
6. CAS Number: 863288-34-0
7. Molecular Formula: \(\mathbf{C_{152}H_{252}N_{44}O_{42}}\)
8. Target: Releasing Hormone Receptor

2. Mechanism of Action

CND10 Without DAC is a short-acting synthetic analog of endogenous Releasing Hormone (GHRH).

1. Binds to GHRH receptors on the anterior pituitary gland, stimulating pulsatile secretion of (GH).
2. Key difference from CND10: No albumin-binding moiety. Shorter half-life, enables controllable, periodic GH spikes, more in line with physiological pulsatile GH secretion pattern.
3. Elevates downstream IGF‑1 concentration, participating in systemic metabolism and tissue remodeling signaling pathways.
4. Works synergistically with peptides,in endocrine research.

3. Research Observed Effects (Laboratory Reference Only)

1. Endocrine research: Simulate physiological pulsatile GH release; study GH/IGF‑1 endocrine axis regulation.
2. Body composition research: Investigate lipolysis promotion, lean muscle protein synthesis in preclinical models.
3. Tissue metabolism research: Explore effects on connective tissue repair and energy metabolism.
4. Anti-aging related basic research: Study the influence of GH pathway on cell senescence.

4. Potential Risks of Bulk Lyophilized Powder

1. No GMP pharmaceutical-grade sterility guarantee. Self-reconstitution and injection may lead to subcutaneous infection, abscess and inflammation.
2. Possible adverse effects for off-label human use: water retention, joint stiffness, flushing, headache.
3. Long-term unsupervised use may disrupt the body’s natural endocrine balance.
4. Uncontrolled impurities and non-pharmaceutical excipients may trigger allergic reactions and increase organ metabolic burden.
5. Legal reminder: This product is limited exclusively to laboratory research. Unauthorized human administration and illegal resale violate pharmaceutical regulations in multiple countries.

6. Storage Specifications

• Long-term storage of dry powder: -20℃, sealed, protected from light, avoid repeated freeze-thaw cycles
• After reconstitution: Store at 2~8°C and consume within a short period