EP10

EP10, also named eL, is a synthetic bioactive tetrapeptide with the amino acid sequence Ala-Glu-Asp-Gly, molecular formula \(\ce{C14H22N4O9}\) and molecular weight of 390.35 Da. Derived from natural pineal gland extract epithalamin, it was developed by Russian gerontologist Professor Vladimir Khavinson for anti-aging research after decades of biological aging studies.Supplied as lyophilized white powder with purity over 98% in 10mg single vials, EP10 is exclusively for laboratory research use and not approved for human medical treatment globally. It targets two core biological systems: chromosomal telomere metabolism and the pineal neuroendocrine axis, functioning as a natural cell bioregulator to delay systematic aging and balance endocrine levels. It needs to be dissolved with bacteriostatic water before subcutaneous injection, and sealed low-temperature storage is required to maintain peptide activity.

2. Four Core Product Efficacy

(1) Activate telomerase & extend cellular lifespan (Anti-senescence)

EP10 uniquely stimulates telomerase activity in human somatic cells, lengthening telomeres that protect chromosome terminals. It breaks the Hayflick limit of cell division, slows cellular senescence and DNA oxidative damage, supports tissue regeneration, and reduces age-related organ function degeneration to achieve systemic anti-aging effects.

(2) Regulate pineal gland & optimize circadian sleep rhythm

It restores the pineal gland’s ability to synthesize MT, reversing the age-related decline of MT secretion. Normalized MT levels stabilize sleep-wake cycles, improve deep sleep quality, relieve insomnia caused by stress or aging, and reduce chronic fatigue triggered by circadian disruption.

(3) Boost immune function & resist inflammatory aging

EP10 modulates the activity of T cells and immune surveillance cells to mitigate immunosenescence. It lowers chronic inflammatory markers in the body, enhances the body’s defense against pathogens, and reduces aging-related inflammatory damage to blood vessels and organs.

(4) Balance neuroendocrine & improve metabolic homeostasis

It optimizes the hypothalamic-pituitary-pineal endocrine axis, normalizing the secretion of gonadotropins and metabolic hormones. Long-term research proves it stabilizes lipid and glucose metabolism, alleviates cardiovascular aging, and improves physical endurance in elderly subjects.