IPA-10

1. Product Code: IPA-10
2. Chemical Name:IPA-10
3. Specification: 10mg per vial
4. Appearance: White sterile lyophilized polypeptide powder
5. Purity: Research grade ≥99% (HPLC verification)
6. CAS Number: 170851-70-4
7. Molecular Formula: (\mathbf{C_{38}H_{49}N_{9}O_{5}}\)
8. Molecular Weight: 711.85 Da
9. Amino Acid Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
10. Target: Ghrelin Receptor (GHS-R1a, Secretagogue Receptor)

2. Mechanism of Action

IPA-10 is a synthetic pentapeptide belonging to Releasing Peptides (GHRPs).

1. Selectively binds to ghrelin receptors in the hypothalamus and pituitary gland, stimulating pulsatile secretion from anterior pituitary.
2. Core advantage: High receptor selectivity. It promotes GH release without obvious elevation of cortisol, prolactin and ACTH, which distinguishes it
3. Indirectly raises IGF-1 levels downstream, participating in tissue metabolism and cell repair signaling pathways.

3. Research Observed Effects (Laboratory Reference Only)

1. Endocrine research: Regulate GH axis, simulate natural pulsatile secretion mode.
2. Body composition research: Promote lipolysis, support lean muscle protein synthesis, reduce fat accumulation in experimental models.
3. Recovery research: Participate in muscle tissue repair, relieve exercise-induced damage.
4. Sleep & metabolism research: Investigated for improving sleep quality and regulating energy metabolism.

4. Potential Risks of Bulk Lyophilized Powder

1. No GMP pharmaceutical sterile standards. Self-reconstitution and injection may trigger subcutaneous infection, abscess and inflammation.
2. Possible adverse reactions in human off-label use: transient nausea, slight appetite increase, headache, water retention.
3. Lack of long-term human safety data; long-term unregulated use may disrupt endocrine balance.
4. Impurities and non-pharmaceutical excipients may induce allergies and organ metabolic burden.
5. Legal reminder: This product is restricted to laboratory research. Unauthorized human application and illegal resale violate drug supervision laws.

5. Storage Specifications

• Dry powder long-term storage: -20℃, sealed, light-proof, avoid repeated freeze-thaw cycles
• After reconstitution: Store at 2~8°C, finish usage within a short period