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Key Specifications/ Special Features
PIN10, also named Pinelon, is a synthetic short tripeptide with the amino acid sequence Glu-Asp-Arg, molecular formula \(\ce{C14H24N6O9}\) and molecular weight around 420.38 Da. It was first developed by Russian gerontologists for neuroendocrine and brain aging research, specifically targeting pineal gland and central nervous system regulation.
Supplied as sterile white lyophilized powder with HPLC-tested purity over 98%, each sealed single vial contains 10 mg peptide powder, hence the code PIN10. This product is strictly limited to laboratory research use only and has not obtained global official approval for human clinical treatment or cosmetic administration. Before subcutaneous injection for trials, PIN10 dry powder needs to be reconstituted with bacteriostatic water. The lyophilized powder requires light-proof, airtight low-temperature storage below -20°C for long-term preservation; once dissolved, the peptide solution maintains stable activity for a maximum of 28 days under refrigeration. It is widely applied in preclinical studies of chronobiology, cognitive aging and neuroprotection.
PIN10 can penetrate the blood-brain barrier to act on pineal gland cells, restoring the gland’s secretory function weakened by aging. It upregulates the synthesis of sleep-regulating hormone, normalizes disrupted sleep-wake cycles, improves deep sleep quality, relieves stress-induced insomnia and chronic fatigue caused by irregular circadian rhythms.
It inhibits excessive free radical production in brain tissue, lowers oxidative stress and hypoxia-induced neuronal apoptosis. The peptide protects brain nerve cells from aging-related degenerative damage, stabilizes mitochondrial function in neurons, and reduces inflammatory injury to the central nervous system in aging models.
Laboratory studies confirm PIN10 modulates DNA and RNA synthesis in brain cells, supports neural tissue repair, and optimizes signal transmission between neurons. It alleviates age-related declines in memory, concentration and learning ability, showing research value for models of mild cognitive impairment and neurodegeneration.
PIN10 regulates the hypothalamic-pineal endocrine axis, correcting age-related imbalance of neuroendocrine hormone secretion. It slows the overall senescence progress of the nervous system, reduces aging biomarkers in brain tissue, and synergistically improves physical vitality alongside sleep and cognitive optimization for systematic anti-aging research.
PIN10, also named Pinelon, is a synthetic short tripeptide with the amino acid sequence Glu-Asp-Arg, molecular formula \(\ce{C14H24N6O9}\) and molecular weight around 420.38 Da. It was first developed by Russian gerontologists for neuroendocrine and brain aging research, specifically targeting pineal gland and central nervous system regulation.
Supplied as sterile white lyophilized powder with HPLC-tested purity over 98%, each sealed single vial contains 10 mg peptide powder, hence the code PIN10. This product is strictly limited to laboratory research use only and has not obtained global official approval for human clinical treatment or cosmetic administration. Before subcutaneous injection for trials, PIN10 dry powder needs to be reconstituted with bacteriostatic water. The lyophilized powder requires light-proof, airtight low-temperature storage below -20°C for long-term preservation; once dissolved, the peptide solution maintains stable activity for a maximum of 28 days under refrigeration. It is widely applied in preclinical studies of chronobiology, cognitive aging and neuroprotection.
PIN10 can penetrate the blood-brain barrier to act on pineal gland cells, restoring the gland’s secretory function weakened by aging. It upregulates the synthesis of sleep-regulating hormone, normalizes disrupted sleep-wake cycles, improves deep sleep quality, relieves stress-induced insomnia and chronic fatigue caused by irregular circadian rhythms.
It inhibits excessive free radical production in brain tissue, lowers oxidative stress and hypoxia-induced neuronal apoptosis. The peptide protects brain nerve cells from aging-related degenerative damage, stabilizes mitochondrial function in neurons, and reduces inflammatory injury to the central nervous system in aging models.
Laboratory studies confirm PIN10 modulates DNA and RNA synthesis in brain cells, supports neural tissue repair, and optimizes signal transmission between neurons. It alleviates age-related declines in memory, concentration and learning ability, showing research value for models of mild cognitive impairment and neurodegeneration.
PIN10 regulates the hypothalamic-pineal endocrine axis, correcting age-related imbalance of neuroendocrine hormone secretion. It slows the overall senescence progress of the nervous system, reduces aging biomarkers in brain tissue, and synergistically improves physical vitality alongside sleep and cognitive optimization for systematic anti-aging research.

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